Ashwagandha is an adaptogen with the strongest evidence profile among all adaptogens, and the KSM-66 extract has the best-quality human trial data. RCT evidence supports: cortisol reduction (8-27% reduction in chronic stress populations), testosterone increase in men (14-17% in double-blind RCTs), anxiety reduction comparable to low-dose benzodiazepines in one trial, and improved thyroid function in subclinical hypothyroidism. The longevity connection is indirect but meaningful: chronic cortisol elevation accelerates cellular aging via telomere shortening and inflammatory signaling. Cortisol management is increasingly viewed as a longevity lever. Dose: 300-600mg KSM-66 daily. Take with food. The one caveat: avoid in autoimmune conditions (theoretical stimulation of immune activity).
Comments on "Ashwagandha (KSM-66)"
Create a free account or sign in to join the discussion.
Sign in to join the conversation